The effect of hydro-alcoholic celery (Apium graveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by. Abstract: Apium graveolens (celery) is an edible and traditionally medicinal plant worldwide, among others for the treatment of hypertension. Celery (Apium graveolens L., Apiaceae) is one of the popular aromatic mean arterial blood pressure and heart rate in normotensive and hypertensive rats.

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Anti-hypertensive Herbs and their Mechanisms of Action: Part I

Fructose, insulin resistance, and metabolic dyslipidemia. Evaluation and treatment of hypertension. Stage 1 and 2 hypertensive humans. Negative control groups group 7 and 8 received NS 0. Effect of celery Apiumgraveolens extracts on some biochemical parameters of oxidative stress hypertensiom mice treated with carbon tetrachloride. Antihypertensive effect of roselle Hibiscus sabdariffa calyx infusion in spontaneously hypertensive rats and a comparison of its toxicity with that in Wistar rats.

Also, the extracts had no graveolems on BP and HR in normotensive groups. TQ’s antihypertensive effects are partly due to its antioxidant activities hyperttension it lowers oxidative stress Khattab and Nagi, ; Ahmad et al. Endothelial function is regulated and maintained by a variety of cell surface receptors, some of which induce the release of vasoactive substances to regulate vascular tone and smooth muscle cell proliferation Drexler and Hornig, In comparable studies, Drobiova et al.


This grant was awarded to AE. Phytochemical, pharmacological and toxicological aspects of Hibiscus sabdariffa L.: Endothelium-dependent and-independent relaxation induced by pinocembrin in rat aortic rings.

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Oxidative stress and vascular damage in hypertension: Rat isolated aortic rings. Inhibitory effects of EAEAg on the contraction and cumulative-contraction. Author information Article notes Copyright and License information Disclaimer. Epigallocatechin gallate attenuates proliferation and oxidative stress in human vascular smooth muscle cells induced by interleukin-1beta via heme oxygenase Renin, angiotensin, sodium and organ damage.

Sprague-Dawley rat aortic rings. Vasorelaxant and antihypertensive effects of methanolic fraction of the essential oil of Alpinia zerumbet.

Chronic N-acetylcysteine prevents fructose-induced insulin resistance and hypertension in rats. BeCl 2 -treated Wistar rats.

aipum Unique vascular protective properties of natural products: This has been highlighted by the ability of black cumin seeds to increase urea, calcium, sodium, and potassium xpium urine of rats Zaoui et al. Cellular effects of garlic supplements and antioxidant vitamins in lowering marginally high blood pressure in humans: Evidence indicates that goldthread, and its main component Berberine BBRhave the ability to lower blood pressure Affuso et al.


All authors contributed to the writing. Similarly, another meta-analysis on randomized, controlled trials also reported a significant decrease in SBP by 4.

There are also other limitations for herbal therapy of hypertension. In the L-NAME-induced hypertension model, the blood pressure decreased after the administration of Crataegus tanacetifolia leaf extract or its isolate, hyperoside.

At lower temperatures, tail blood flow was reduced and determination of BP was very difficult.

Circulation— Support Center Support Center. Molecules 17— Human umbilical vein endothelial cells. A probable explanation for this phenomenon is the varied action of different ginsenosides Valli and Giardina, Dihydrotanshinone, a lipophilic component of Salvia miltiorrhiza danshenrelaxes rat coronary artery by inhibition of calcium channels. Phytomedicine 19— Pharmacological actions of pungent constitutents, 6 -gingerol and 6 -shogaol.